The Tigray Region (Tigrinya: ክልል ትግራይ, kilil Tigrāy; Official name: Tigrinya: ብሄራዊ ክልላዊ መንግስቲ ትግራይ, Bəh̩erawi Kəllelawi Mängəśti Təgray, English: Tigray National Regional State") is the northernmost of the nine regions (kililat) of Ethiopia. Tigray is the homeland of the Tigrayan, Irob and Kunama peoples. Tigray is also known as Region 1 according to the federal constitution. Its capital and largest city is Mekelle. Tigray is the 6th largest by area, the 3rd most populous, and the 5th most densely populated of the 9 Regional States.

Tigray's official language is Tigrigna. Tigray is situated between 12°–15° N and 36° 30' – 40° 30' E and comprises 53,638 square kilometres (20,710 sq mi)^[4] Tigray has ca. 8.3 million inhabitants. The greatest part of the population (ca. 80%) are agriculturalists, contributing 46% to the regional gross domestic product (2002/03). The highlands (11.5% dəgʷəa, 40.5% wäyna däga) have the highest population density, specially in eastern and central Tigray. The much less densely populated lowlands of Tigray (qʷälla) comprise 48% of Tigray.

Tigray is bordered by Eritrea to the north, Sudan to the west, the Amhara Region to the south and the Afar Region to the east and south east.^[5] Besides Mekelle, major cities include Adigrat, Aksum, Shire, Humera, Adwa, Adi Remets, Alamata, Wukro, Maychew, Sheraro, Abiy Adi, Korem, Qwiha, Atsbi, Hawzen, Mekoni,Dansha and Zalambessa. There is also the historically significant town of Yeha.

The government of Tigray is composed of the executive branch, led by the President; the legislative branch, which comprises the State Council; and the judicial branch, which is led by the state Supreme Court.